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art-1 putative very-long-chain enoyl-CoA reductase art-1 [ Caenorhabditis elegans ]

Gene ID: 174140, updated on 2-Nov-2024

Summary

Official Symbol
art-1
Official Full Name
putative very-long-chain enoyl-CoA reductase art-1
Primary source
WormBase:WBGene00000198
Locus tag
CELE_C15F1.6
See related
AllianceGenome:WB:WBGene00000198
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 14 and catecholaminergic polymorphic ventricular tachycardia 3. Orthologous to several human genes including TECR (trans-2,3-enoyl-CoA reductase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See art-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (6970745..6972235, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Superoxide dismutase [Cu-Zn] Neighboring gene Ribosomal protein L29

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
enables very-long-chain enoyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in very long-chain fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative very-long-chain enoyl-CoA reductase art-1
NP_495430.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6970745..6972235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063029.7NP_495430.1  putative very-long-chain enoyl-CoA reductase art-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495430.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N5Y2
    Conserved Domains (3) summary
    cd01801
    Location:582
    Tsc13_N; Ubiquitin-like domain of Tsc13
    PLN02560
    Location:23307
    PLN02560; enoyl-CoA reductase
    cl21511
    Location:155308
    PEMT; Phospholipid methyltransferase