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acs-6 fatty Acid CoA Synthetase family [ Caenorhabditis elegans ]

Gene ID: 174156, updated on 2-Nov-2024

Summary

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Official Symbol
acs-6
Official Full Name
fatty Acid CoA Synthetase family
Primary source
WormBase:WBGene00022849
Locus tag
CELE_ZK1127.2
See related
AllianceGenome:WB:WBGene00022849
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable CoA-ligase activity. Predicted to be located in peroxisome. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acs-6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (7062030..7064777)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein BCCIP homolog Neighboring gene Uncharacterized protein Neighboring gene Putative cystathionine gamma-lyase 2 Neighboring gene MutS protein homolog him-14 Neighboring gene Nanos-type domain-containing protein Neighboring gene Lysine--tRNA ligase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Di(2-ethylhexyl) phthalate and diethyl phthalate disrupt lipid metabolism, reduce fecundity and shortens lifespan of Caenorhabditis elegans. Pradhan A, et al. Chemosphere, 2018 Jan. PMID 29020644
  2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables CoA-ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
fatty Acid CoA Synthetase family
NP_495450.1
  • Product from WormBase gene class acs;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7062030..7064777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063049.5 → NP_495450.1  fatty Acid CoA Synthetase family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495450.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23404
    Conserved Domains (2) summary
    cd05911
    Location:37 → 532
    Firefly_Luc_like; Firefly luciferase of light emitting insects and 4-Coumarate-CoA Ligase (4CL)
    COG0318
    Location:15 → 541
    CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
Nucleotide Protein
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