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F10E7.9 Amino acid permease/ SLC12A domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174167, updated on 2-Nov-2024

Summary

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Official Symbol
F10E7.9
Official Full Name
Amino acid permease/ SLC12A domain-containing protein
Primary source
WormBase:WBGene00017350
Locus tag
CELE_F10E7.9
See related
AllianceGenome:WB:WBGene00017350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Predicted to be located in membrane. Is expressed in nerve ring; retrovesicular ganglion neurons; and tail neurons. Orthologous to human SLC12A8 (solute carrier family 12 member 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F10E7.9 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (7106412..7110056, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DUF3402 domain-containing protein;Far11/STRP C-terminal domain-containing protein Neighboring gene Large ribosomal subunit protein eL33 Neighboring gene Ribosome assembly factor mrt4 Neighboring gene Uncharacterized protein Neighboring gene ZP domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chloride:monoatomic cation symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables potassium:chloride symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell volume homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chloride ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Amino acid permease/ SLC12A domain-containing protein
NP_495469.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7106412..7110056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063068.8 → NP_495469.2  Amino acid permease/ SLC12A domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495469.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19301
    Conserved Domains (1) summary
    TIGR00930
    Location:47 → 557
    2a30; K-Cl cotransporter
Nucleotide Protein
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