U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

T13H5.1 Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174359, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
T13H5.1
Official Full Name
Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein
Primary source
WormBase:WBGene00011755
Locus tag
CELE_T13H5.1
See related
AllianceGenome:WB:WBGene00011755
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction and synaptic membrane adhesion. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A) and PTPRE (protein tyrosine phosphatase receptor type E). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See T13H5.1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
28
Sequence:
Chromosome: II; NC_003280.10 (8487513..8509056, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene HIG1 domain-containing protein Neighboring gene TAil-Anchored Protein Neighboring gene Trimethyllysine dioxygenase, mitochondrial Neighboring gene ncRNA Neighboring gene DB domain-containing protein Neighboring gene CRAL-TRIO domain-containing protein Neighboring gene Ribonuclease H2 subunit A

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synaptic membrane adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein
NP_001022346.2
  • Confirmed by transcript evidence
NP_001022347.1
  • Confirmed by transcript evidence
NP_001122640.1
  • Confirmed by transcript evidence
NP_001129824.1
  • Confirmed by transcript evidence
NP_001129825.1
  • Partially confirmed by transcript evidence
NP_001254153.1
  • Confirmed by transcript evidence
NP_001254154.1
  • Confirmed by transcript evidence
NP_001254155.1
  • Confirmed by transcript evidence
NP_001379493.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8487513..8509056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027175.4 → NP_001022346.2  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022346.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGI0
    Conserved Domains (2) summary
    smart00194
    Location:206 → 465
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:233 → 465
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  2. NM_001136352.5 → NP_001129824.1  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001129824.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGJ3
    Conserved Domains (2) summary
    smart00194
    Location:93 → 352
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:120 → 352
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  3. NM_001136353.3 → NP_001129825.1  Receptor-type tyrosine-protein phosphatase mu [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001129825.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGM6
    Conserved Domains (2) summary
    smart00194
    Location:66 → 325
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:93 → 325
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  4. NM_001129168.4 → NP_001122640.1  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122640.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC69
    Conserved Domains (3) summary
    smart00194
    Location:206 → 465
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:233 → 465
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cl21483
    Location:528 → 796
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  5. NM_001267225.3 → NP_001254154.1  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254154.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECI6
    Conserved Domains (2) summary
    smart00194
    Location:162 → 421
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:189 → 421
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  6. NM_001393137.1 → NP_001379493.1  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEM4
    Conserved Domains (1) summary
    smart00194
    Location:155 → 414
    PTPc; Protein tyrosine phosphatase, catalytic domain

  7. NM_001267226.3 → NP_001254155.1  Receptor-type tyrosine-protein phosphatase mu [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254155.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EG42
    Conserved Domains (2) summary
    smart00194
    Location:57 → 316
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:84 → 316
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  8. NM_001027176.5 → NP_001022347.1  Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022347.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EFE8
    Conserved Domains (2) summary
    smart00194
    Location:114 → 373
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:141 → 373
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  9. NM_001267224.3 → NP_001254153.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254153.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F5GU90
    Conserved Domains (1) summary
    cl21483
    Location:25 → 127
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.