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col-38 Cuticle collagen 38 [ Caenorhabditis elegans ]

Gene ID: 174370, updated on 2-Nov-2024

Summary

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Official Symbol
col-38
Official Full Name
Cuticle collagen 38
Primary source
WormBase:WBGene00000615
Locus tag
CELE_F54C9.4
See related
AllianceGenome:WB:WBGene00000615
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in nucleus. Is expressed in hyp7 syncytium and seam cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See col-38 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (8568035..8569088, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of C. elegans L4 cuticle collagen genes by the heterochronic protein LIN-29. Abete-Luzi P, et al. Genesis, 2018 May. PMID 29604168, Free PMC Article
  2. Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development. Jackson BM, et al. G3 (Bethesda), 2014 Apr 16. PMID 24569038, Free PMC Article
  3. Ketamine induces apical extracellular matrix modifications in Caenorhabditis elegans. Yücel D. Sci Rep, 2022 Dec 21. PMID 36543791, Free PMC Article
  4. New Roles for the Heterochronic Transcription Factor LIN-29 in Cuticle Maintenance and Lipid Metabolism at the Larval-to-Adult Transition in Caenorhabditis elegans. Abete-Luzi P, et al. Genetics, 2020 Mar. PMID 31974205, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in collagen and cuticulin-based cuticle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cuticle collagen 38
NP_495810.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8568035..8569088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063409.7 → NP_495810.1  Cuticle collagen 38 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495810.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20754
    Conserved Domains (2) summary
    pfam01391
    Location:144 → 197
    Collagen; Collagen triple helix repeat (20 copies)
    smart01088
    Location:4 → 56
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q20754.2

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