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pigg-1 GPI ethanolamine phosphate transferase 2 [ Caenorhabditis elegans ]

Gene ID: 174377, updated on 2-Nov-2024

Summary

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Official Symbol
pigg-1
Official Full Name
GPI ethanolamine phosphate transferase 2
Primary source
WormBase:WBGene00009204
Locus tag
CELE_F28C6.4
See related
AllianceGenome:WB:WBGene00009204
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable CP2 mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pigg-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
11
Sequence:
Chromosome: II; NC_003280.10 (8596275..8600265, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like protein 1 Neighboring gene GDP/GTP exchange factor Sec2 N-terminal domain-containing protein Neighboring gene Transcription factor aptf-4 Neighboring gene Transcription factor AP-2 C-terminal domain-containing protein Neighboring gene Amelotin Neighboring gene Cleavage stimulation factor 50 kDa subunit Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL24

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables CP2 mannose-ethanolamine phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannose-ethanolamine phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GPI ethanolamine phosphate transferase 2
NP_001022123.1
  • Confirmed by transcript evidence
NP_001367076.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8596275..8600265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026952.4 → NP_001022123.1  GPI ethanolamine phosphate transferase 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022123.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19870
    Conserved Domains (1) summary
    cd16024
    Location:54 → 328
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G

  2. NM_001381530.2 → NP_001367076.1  GPI ethanolamine phosphate transferase 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JM05
    Conserved Domains (1) summary
    cd16024
    Location:54 → 328
    GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
Nucleotide Protein
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