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cpf-1 Cleavage stimulation factor 50 kDa subunit [ Caenorhabditis elegans ]

Gene ID: 174378, updated on 2-Nov-2024

Summary

Official Symbol
cpf-1
Official Full Name
Cleavage stimulation factor 50 kDa subunit
Primary source
WormBase:WBGene00000773
Locus tag
CELE_F28C6.3
See related
AllianceGenome:WB:WBGene00000773
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage stimulating factor complex. Orthologous to human CSTF1 (cleavage stimulation factor subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See cpf-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (8600449..8602440, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transcription factor aptf-4 Neighboring gene Transcription factor AP-2 C-terminal domain-containing protein Neighboring gene GPI ethanolamine phosphate transferase 2 Neighboring gene Amelotin Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL24 Neighboring gene Suppressor of forked domain-containing protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mRNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of mRNA cleavage stimulating factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mRNA cleavage stimulating factor complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Cleavage stimulation factor 50 kDa subunit
NP_495822.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8600449..8602440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063421.7NP_495822.1  Cleavage stimulation factor 50 kDa subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495822.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19864
    Conserved Domains (3) summary
    cd00200
    Location:101421
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:114168
    7WD40; WD40 repeat [structural motif]
    pfam16699
    Location:360
    CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerization domain