F28C6.8 TYR_PHOSPHATASE_2 domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F28C6.8
Official Full Name: TYR_PHOSPHATASE_2 domain-containing protein
Primary source: WormBase:WBGene00009207
Locus tag: CELE_F28C6.8
See related: AllianceGenome:WB:WBGene00009207
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphatidylinositol phosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol catabolic process. Orthologous to human PTPMT1 (protein tyrosine phosphatase mitochondrial 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F28C6.8 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 2

Sequence:: Chromosome: II; NC_003280.10 (8606849..8607749)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F28C6.6 (e-PCR)
- UniSTS:307556

F28C6.8 (e-PCR)
- UniSTS:320946

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables phosphatidylglycerophosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol phosphate 5-phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in dephosphorylation	IEA Inferred from Electronic Annotation more info
involved_in phosphatidylinositol catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TYR_PHOSPHATASE_2 domain-containing protein

NP_001254161.1

Confirmed by transcript evidence

NP_001254162.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

8606849..8607749

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001267232.2 → NP_001254161.1 TYR_PHOSPHATASE_2 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254161.1

Status: REVIEWED

UniProtKB/TrEMBL

I2HA91

Conserved Domains (1) summary

pfam00782
Location:49 → 175

DSPc; Dual specificity phosphatase, catalytic domain
NM_001267233.3 → NP_001254162.1 TYR_PHOSPHATASE_2 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254162.1

Status: REVIEWED

UniProtKB/TrEMBL

Q93622

Conserved Domains (1) summary

pfam00782
Location:10 → 136

DSPc; Dual specificity phosphatase, catalytic domain