dnj-20 DnaJ homolog dnj-20 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: dnj-20
Gene description: DnaJ homolog dnj-20
Locus tag: CELE_T15H9.7
See related: AllianceGenome:WB:WBGene00001038
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Is expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in polycystic kidney disease. Orthologous to human DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See dnj-20 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 8

Sequence:: Chromosome: II; NC_003280.10 (9617469..9624176, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T15H9.1 (e-PCR)
- UniSTS:315000

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables misfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein folding	IEA Inferred from Electronic Annotation more info
involved_in protein maturation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DnaJ homolog dnj-20

NP_001370249.1

Confirmed by transcript evidence

NP_496072.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

9617469..9624176 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001383920.2 → NP_001370249.1 DnaJ homolog dnj-20 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

B3GWA8, Q10005, Q8MPX3

Conserved Domains (1) summary

COG0484
Location:23 → 350

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
NM_063671.7 → NP_496072.2 DnaJ homolog dnj-20 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496072.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8MPX3

Conserved Domains (1) summary

cl21722
Location:1 → 54

DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40