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flp-4 FMRF-Like Peptide [ Caenorhabditis elegans ]

Gene ID: 174568, updated on 2-Nov-2024

Summary

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Official Symbol
flp-4
Official Full Name
FMRF-Like Peptide
Primary source
WormBase:WBGene00001447
Locus tag
CELE_C18D1.3
See related
AllianceGenome:WB:WBGene00001447
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in nerve ring; pharyngeal neurons; and sensory neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See flp-4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (10048868..10055561)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SPK domain-containing protein Neighboring gene BTB and MATH domain-containing protein 38 Neighboring gene Uncharacterized protein Neighboring gene STarGazin (mammalian calcium channel) homolog Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and regulation of an FMRFamide-related neuropeptide gene family in Caenorhabditis elegans. Kim K, et al. J Comp Neurol, 2004 Aug 2. PMID 15236235
  2. FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans. Yu Y, et al. Sci Rep, 2016 Feb 18. PMID 26887501, Free PMC Article
  3. Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans. Reinitz CA, et al. Mol Biochem Parasitol, 2000 Nov. PMID 11087928
  4. FMRFamide-related peptides (FaRPs) in nematodes: occurrence and neuromuscular physiology. Maule AG, et al. Parasitology, 1996. PMID 9051931
  5. Improved statistical model checking methods for pathway analysis. Koh CH, et al. BMC Bioinformatics, 2012. PMID 23282174, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FMRF-Like Peptide
NP_001379072.1
  • Product from WormBase gene class flp;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10048868..10055561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393175.1 → NP_001379072.1  FMRF-Like Peptide [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EG31
Nucleotide Protein
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