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daf-19 RFX-like transcription factor daf-19 [ Caenorhabditis elegans ]

Gene ID: 174577, updated on 2-Nov-2024

Summary

Official Symbol
daf-19
Official Full Name
RFX-like transcription factor daf-19
Primary source
WormBase:WBGene00000914
Locus tag
CELE_F33H1.1
See related
AllianceGenome:WB:WBGene00000914
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to Gram-negative bacterium; male mating behavior; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within serotonin biosynthetic process. Located in nucleus. Is expressed in several structures, including body wall musculature; hypodermis; intestine; neurons; and somatic nervous system. Orthologous to several human genes including RFX3 (regulatory factor X3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See daf-19 in Genome Data Viewer
Location:
chromosome: II
Exon count:
13
Sequence:
Chromosome: II; NC_003280.10 (10157520..10169346, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Paired box protein 3 homolog Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase 4 Neighboring gene Ww (WW) domain Binding Protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RFX-like transcription factor daf-19
NP_001022139.1
  • Confirmed by transcript evidence
NP_001022140.1
  • Confirmed by transcript evidence
NP_001254236.1
  • Confirmed by transcript evidence
NP_001254237.1
  • Confirmed by transcript evidence
NP_001293485.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10157520..10169346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267307.5NP_001254236.1  RFX-like transcription factor daf-19 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254236.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C0P280
    Conserved Domains (1) summary
    pfam02257
    Location:113190
    RFX_DNA_binding; RFX DNA-binding domain
  2. NM_001026969.4NP_001022140.1  RFX-like transcription factor daf-19 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022140.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0P280, G5EBW8, Q09555, Q9NHC9, S6EZR7
    Conserved Domains (1) summary
    pfam02257
    Location:257332
    RFX_DNA_binding; RFX DNA-binding domain
  3. NM_001026968.5NP_001022139.1  RFX-like transcription factor daf-19 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022139.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09555
    Conserved Domains (1) summary
    pfam02257
    Location:232307
    RFX_DNA_binding; RFX DNA-binding domain
  4. NM_001306556.3NP_001293485.1  RFX-like transcription factor daf-19 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293485.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    S6EZR7
    Conserved Domains (1) summary
    pfam02257
    Location:91165
    RFX_DNA_binding; RFX DNA-binding domain
  5. NM_001267308.3NP_001254237.1  RFX-like transcription factor daf-19 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254237.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBW8
    Conserved Domains (1) summary
    pfam02257
    Location:75149
    RFX_DNA_binding; RFX DNA-binding domain