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R166.2 Cleft lip and palate transmembrane protein 1 homolog [ Caenorhabditis elegans ]

Gene ID: 174620, updated on 18-Sep-2024

Summary

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Official Symbol
R166.2
Official Full Name
Cleft lip and palate transmembrane protein 1 homolog
Primary source
WormBase:WBGene00011302
Locus tag
CELE_R166.2
See related
AllianceGenome:WB:WBGene00011302
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in body wall musculature; hypodermis; intestine; and nervous system. Orthologous to human CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See R166.2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (10534332..10537671, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene NAB transcription cofactor mab-10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Pre-rRNA-processing protein pro-1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cleft lip and palate transmembrane protein 1 homolog
NP_496269.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10534332..10537671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063868.5 → NP_496269.1  Cleft lip and palate transmembrane protein 1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496269.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22003
    Conserved Domains (1) summary
    pfam05602
    Location:27 → 471
    CLPTM1; Cleft lip and palate transmembrane protein 1 (CLPTM1)
Nucleotide Protein
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