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set-14 SET domain-containing protein 14 [ Caenorhabditis elegans ]

Gene ID: 174662, updated on 2-Nov-2024

Summary

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Official Symbol
set-14
Official Full Name
SET domain-containing protein 14
Primary source
WormBase:WBGene00011068
Locus tag
CELE_R06F6.4
See related
AllianceGenome:WB:WBGene00011068
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be active in nucleus. Is expressed in germ line; hypodermis; intestine; and neurons. Orthologous to human SMYD1 (SET and MYND domain containing 1) and SMYD2 (SET and MYND domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See set-14 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (10793595..10796294, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Putative protein tag-209 Neighboring gene Vacuolar protein sorting-associated protein 11 homolog Neighboring gene Nucleoporin NUP35 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
  2. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190
  3. Epigenetics in C. elegans: facts and challenges. Wenzel D, et al. Genesis, 2011 Aug. PMID 21538806
  4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SET domain-containing protein 14
NP_496323.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10793595..10796294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063922.7 → NP_496323.1  SET domain-containing protein 14 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496323.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09414, Q09415
    Conserved Domains (1) summary
    pfam01753
    Location:26 → 64
    zf-MYND; MYND finger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09415.2

Gene LinkOut

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