metl-1 tRNA (guanine-N(7)-)-methyltransferase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: metl-1
Official Full Name: tRNA (guanine-N(7)-)-methyltransferase
Primary source: WormBase:WBGene00012205
Locus tag: CELE_W02B12.10
See related: AllianceGenome:WB:WBGene00012205
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable tRNA (guanine(46)-N7)-methyltransferase activity. Predicted to be involved in RNA (guanine-N7)-methylation and tRNA methylation. Predicted to be located in nucleus. Predicted to be part of tRNA methyltransferase complex. Is expressed in several structures, including excretory cell; intestine; nervous system; pharynx; and reproductive system. Orthologous to human METTL1 (methyltransferase 1, tRNA methylguanosine). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (guanine(46)-N7)-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables tRNA (guanine(46)-N7)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (guanine(46)-N7)-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA (guanine-N7)-methylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA (guanine-N7)-methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA methylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA modification	IEA Inferred from Electronic Annotation more info
involved_in tRNA modification	ISS Inferred from Sequence or Structural Similarity more info
involved_in tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of tRNA methyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

NP_496448.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain