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W02B12.11 Beta-1,4-N-acetylgalactosaminyltransferase [ Caenorhabditis elegans ]

Gene ID: 174754, updated on 2-Nov-2024

Summary

Official Symbol
W02B12.11
Official Full Name
Beta-1,4-N-acetylgalactosaminyltransferase
Primary source
WormBase:WBGene00012206
Locus tag
CELE_W02B12.11
See related
AllianceGenome:WB:WBGene00012206
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity and beta-1,4-N-acetylgalactosaminyltransferase activity. Predicted to be involved in glycosphingolipid biosynthetic process and protein glycosylation. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See W02B12.11 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (11473861..11476025)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Mitoferrin Neighboring gene tRNA (guanine-N(7)-)-methyltransferase Neighboring gene Uncharacterized protein Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables beta-1,4-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycosphingolipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Beta-1,4-N-acetylgalactosaminyltransferase
NP_496449.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11473861..11476025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064048.7NP_496449.1  Beta-1,4-N-acetylgalactosaminyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496449.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGS9
    Conserved Domains (1) summary
    cd00899
    Location:158375
    b4GalT; Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids