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coa-7 Cytochrome c oxidase assembly factor 7 homolog [ Caenorhabditis elegans ]

Gene ID: 174784, updated on 2-Nov-2024

Summary

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Official Symbol
coa-7
Official Full Name
Cytochrome c oxidase assembly factor 7 homolog
Primary source
WormBase:WBGene00013925
Locus tag
CELE_ZK20.4
See related
AllianceGenome:WB:WBGene00013925
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in spinocerebellar ataxia with axonal neuropathy type 3. Orthologous to human COA7 (cytochrome c oxidase assembly factor 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See coa-7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (11649096..11651148, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Glycoprotein Hormone (FLR-2) Interacting protein Neighboring gene UV excision repair protein RAD23 Neighboring gene 26S proteasome non-ATPase regulatory subunit 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Cytochrome c oxidase assembly factor 7 homolog
NP_496487.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11649096..11651148 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064086.5 → NP_496487.1  Cytochrome c oxidase assembly factor 7 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496487.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23450
    Conserved Domains (2) summary
    COG0790
    Location:48 → 231
    TPR; TPR repeat [Signal transduction mechanisms]
    sd00010
    Location:128 → 156
    SLR; SLR repeat [structural motif]

RNA

  1. NR_024299.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q23450.1

Gene LinkOut

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