U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mex-1 C3H1-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174836, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
mex-1
Official Full Name
C3H1-type domain-containing protein
Primary source
WormBase:WBGene00003228
Locus tag
CELE_W03C9.7
See related
AllianceGenome:WB:WBGene00003228
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; establishment of cell polarity; and formation of primary germ layer. Located in P granule. Is expressed in several structures, including C; D; EMS; germ line; and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See mex-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (11968637..11972347)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Ras-related protein Rab-7a Neighboring gene PTK2 Neighboring gene ACB domain-containing protein Neighboring gene BZIP domain-containing protein;Regulator of rDNA transcription 14 Neighboring gene BZIP domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cellular interactions involved in the determination of the early C. elegans embryo. Schnabel R. Mech Dev, 1991 Jun. PMID 1911397
  2. Effects of chromosomal deficiencies on early cleavage patterning and terminal phenotype in Caenorhabditis elegans embryos. Storfer-Glazer FA, et al. Genetics, 1994 Jun. PMID 8070660, Free PMC Article
  3. An analysis of the response to gut induction in the C. elegans embryo. Goldstein B. Development, 1995 Apr. PMID 7743934
  4. Molecular basis of RNA recognition by the embryonic polarity determinant MEX-5. Pagano JM, et al. J Biol Chem, 2007 Mar 23. PMID 17264081
  5. Why does a nematode have an invariant cell lineage? Schnabel R. Semin Cell Dev Biol, 1997 Aug. PMID 15001072

See all (79) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell fate specification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in embryonic pattern specification IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in embryonic pattern specification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in formation of primary germ layer IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
C3H1-type domain-containing protein
NP_001254325.1
  • Confirmed by transcript evidence
NP_001254326.1
  • Confirmed by transcript evidence
NP_001391110.1
  • Confirmed by transcript evidence
NP_001391129.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11968637..11972347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001404252.1 → NP_001391110.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S4QD38

  2. NM_001267396.4 → NP_001254325.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254325.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECB9
    Conserved Domains (1) summary
    pfam00642
    Location:139 → 165
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  3. NM_001404254.1 → NP_001391129.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S4QB40

  4. NM_001267397.3 → NP_001254326.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254326.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2HJZ1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous