Y17G7B.18 putative RNA methyltransferase Y17G7B.18 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y17G7B.18
Official Full Name: putative RNA methyltransferase Y17G7B.18
Primary source: WormBase:WBGene00012469
Locus tag: CELE_Y17G7B.18
See related: AllianceGenome:WB:WBGene00012469
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable O-methyltransferase activity; RNA methyltransferase activity; and snRNA binding activity. Predicted to be involved in snRNA modification. Orthologous to human MEPCE (methylphosphate capping enzyme). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y17G7B.18 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (12103331..12107857, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y17G7B.18a (e-PCR)
- UniSTS:320157

Y17G7B.19 (e-PCR)
- UniSTS:312824

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables O-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables snRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info
involved_in snRNA modification	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative RNA methyltransferase Y17G7B.18

NP_001379028.1

Partially confirmed by transcript evidence

NP_496573.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

12103331..12107857 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001393208.1 → NP_001379028.1 putative RNA methyltransferase Y17G7B.18 [Caenorhabditis elegans]

Status: REVIEWED

Conserved Domains (2) summary

pfam06859
Location:260 → 367

Bin3; Bicoid-interacting protein 3 (Bin3)

pfam13649
Location:156 → 296

Methyltransf_25; Methyltransferase domain
NM_064172.5 → NP_496573.1 putative RNA methyltransferase Y17G7B.18 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496573.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9U2R0, Q9XXH6

Conserved Domains (2) summary

pfam06859
Location:257 → 364

Bin3; Bicoid-interacting protein 3 (Bin3)

pfam12847
Location:153 → 299

Methyltransf_18; Methyltransferase domain