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Y48C3A.18 Threonylcarbamoyl-AMP synthase [ Caenorhabditis elegans ]

Gene ID: 174981, updated on 2-Nov-2024

Summary

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Official Symbol
Y48C3A.18
Official Full Name
Threonylcarbamoyl-AMP synthase
Primary source
WormBase:WBGene00012997
Locus tag
CELE_Y48C3A.18
See related
AllianceGenome:WB:WBGene00012997
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable nucleotidyltransferase activity and tRNA binding activity. Predicted to be involved in regulation of translational fidelity. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Orthologous to human YRDC (yrdC N6-threonylcarbamoyltransferase domain containing). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y48C3A.18 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (13412635..13414906)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Peptidyl-prolyl cis-trans isomerase Neighboring gene Transcription factor efl-2 Neighboring gene Centromere protein S;Eukaryotic translation initiation factor 3 30 kDa subunit Neighboring gene Carnosine N-methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotidyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Threonylcarbamoyl-AMP synthase
NP_001122661.2
  • Partially confirmed by transcript evidence
NP_001254385.1
  • Confirmed by transcript evidence
NP_496826.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13412635..13414906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064425.4 → NP_496826.2  Threonylcarbamoyl-AMP synthase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496826.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NAF8
    Conserved Domains (1) summary
    pfam01300
    Location:28 → 197
    Sua5_yciO_yrdC; Telomere recombination

  2. NM_001129189.4 → NP_001122661.2  Threonylcarbamoyl-AMP synthase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122661.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5HWA9
    Conserved Domains (1) summary
    cl00305
    Location:9 → 124
    Sua5_yciO_yrdC; Telomere recombination

  3. NM_001267456.3 → NP_001254385.1  Threonylcarbamoyl-AMP synthase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254385.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2HK06
    Conserved Domains (1) summary
    cl00305
    Location:8 → 100
    Sua5_yciO_yrdC; Telomere recombination
Nucleotide Protein
Heading Accession and Version

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