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Y48E1C.1 Centromere protein S;Eukaryotic translation initiation factor 3 30 kDa subunit [ Caenorhabditis elegans ]

Gene ID: 174982, updated on 2-Nov-2024

Summary

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Official Symbol
Y48E1C.1
Official Full Name
Centromere protein S;Eukaryotic translation initiation factor 3 30 kDa subunit
Primary source
WormBase:WBGene00013014
Locus tag
CELE_Y48E1C.1
See related
AllianceGenome:WB:WBGene00013014
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in replication fork processing and resolution of meiotic recombination intermediates. Predicted to be part of FANCM-MHF complex. Orthologous to human CENPS-CORT (CENPS-CORT readthrough) and CENPS (centromere protein S). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y48E1C.1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (13415007..13424449)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transcription factor efl-2 Neighboring gene Threonylcarbamoyl-AMP synthase Neighboring gene Carnosine N-methyltransferase Neighboring gene SnoaL-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pairing centers recruit a Polo-like kinase to orchestrate meiotic chromosome dynamics in C. elegans. Harper NC, et al. Dev Cell, 2011 Nov 15. PMID 22018922, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in replication fork processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in resolution of meiotic recombination intermediates IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of FANCM-MHF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of FANCM-MHF complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Centromere protein S;Eukaryotic translation initiation factor 3 30 kDa subunit
NP_001254386.1
  • Confirmed by transcript evidence
NP_496828.1
  • Confirmed by transcript evidence
NP_871968.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13415007..13424449
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_182168.5 → NP_871968.1  Eukaryotic translation initiation factor 3 30 kDa subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871968.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBR6

  2. NM_064427.7 → NP_496828.1  Centromere protein S [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC81
    Conserved Domains (2) summary
    pfam03342
    Location:219 → 321
    Rhabdo_M1; Rhabdovirus M1 matrix protein (M1 polymerase-associated protein)
    pfam15630
    Location:37 → 119
    CENP-S; Kinetochore component CENP-S

  3. NM_001267457.3 → NP_001254386.1  Centromere protein S [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254386.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBV2
    Conserved Domains (2) summary
    pfam03342
    Location:154 → 256
    Rhabdo_M1; Rhabdovirus M1 matrix protein (M1 polymerase-associated protein)
    pfam15630
    Location:14 → 54
    CENP-S; Kinetochore component CENP-S

RNA

  1. NR_144482.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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