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his-15 Histone H2B 1 [ Caenorhabditis elegans ]

Gene ID: 175026, updated on 2-Nov-2024

Summary

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Official Symbol
his-15
Official Full Name
Histone H2B 1
Primary source
WormBase:WBGene00001889
Locus tag
CELE_ZK131.9
See related
AllianceGenome:WB:WBGene00001889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC12 (H2B clustered histone 12); and H2BC17 (H2B clustered histone 17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See his-15 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003280.10 (13818371..13818739)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Neogenin_C domain-containing protein;TORC_N domain-containing protein Neighboring gene ncRNA Neighboring gene Histone H2A Neighboring gene ncRNA Neighboring gene Histone H4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequences of Caenorhabditis elegans core histone genes. Genes for different histone classes share common flanking sequence elements. Roberts SB, et al. J Mol Biol, 1989 Apr 20. PMID 2544730
  2. Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures. Beer KB, et al. Nat Commun, 2019 Aug 2. PMID 31375709, Free PMC Article
  3. Visualizing Phagocytic Cargo In Vivo from Engulfment to Resolution in Caenorhabditis elegans. Fazeli G, et al. Methods Mol Biol, 2023. PMID 37365478
  4. Evidence for dynamic alteration in histone gene clusters of Caenorhabditis elegans: a topoisomerase II connection? Holt SJ, et al. Genet Res, 2002 Feb. PMID 11974600
  5. Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B. Liu Y, et al. Structure, 2019 Dec 3. PMID 31653339

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in innate immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H2B 1
NP_496888.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13818371..13818739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064487.1 → NP_496888.1  Histone H2B 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496888.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02656, P04255
    Conserved Domains (1) summary
    smart00427
    Location:24 → 120
    H2B; Histone H2B
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P04255.4

Gene LinkOut

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