U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

his-26 Histone H4 [ Caenorhabditis elegans ]

Gene ID: 175032, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
his-26
Official Full Name
Histone H4
Primary source
WormBase:WBGene00001900
Locus tag
CELE_ZK131.1
See related
AllianceGenome:WB:WBGene00001900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Orthologous to several human genes including H4C1 (H4 clustered histone 1); H4C11 (H4 clustered histone 11); and H4C12 (H4 clustered histone 12). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See his-26 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003280.10 (13825532..13825843)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene Histone H3 Neighboring gene Histone H2B 1 Neighboring gene Histone H2A

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hypoxia-inducible Factor-1 (HIF-1)-independent hypoxia response of the small heat shock protein hsp-16.1 gene regulated by chromatin-remodeling factors in the nematode Caenorhabditis elegans. Lee J, et al. J Biol Chem, 2013 Jan 18. PMID 23229554, Free PMC Article
  2. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article
  3. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Jackson J, et al. Mol Metab, 2022 Jul. PMID 35452878, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Histone H4
NP_496896.1
  • Predicted

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13825532..13825843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064495.1 → NP_496896.1  Histone H4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496896.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02619, P62784, Q7JNV2
    Conserved Domains (1) summary
    PLN00035
    Location:1 → 103
    PLN00035; histone H4; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62784.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.