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hda-10 Histone deacetylase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175039, updated on 2-Nov-2024

Summary

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Official Symbol
hda-10
Official Full Name
Histone deacetylase domain-containing protein
Primary source
WormBase:WBGene00001838
Locus tag
CELE_Y51H1A.5
See related
AllianceGenome:WB:WBGene00001838
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable histone deacetylase activity. Predicted to be involved in epigenetic regulation of gene expression. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC10 (histone deacetylase 10). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hda-10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (13882705..13888034)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Neighboring gene Inhibitor of growth protein Neighboring gene Modifier of cell death Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans ing-3 gene regulates ionizing radiation-induced germ-cell apoptosis in a p53-associated pathway. Luo J, et al. Genetics, 2009 Feb. PMID 19015549, Free PMC Article
  2. Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis. Dufourcq P, et al. Mol Cell Biol, 2002 May. PMID 11940660, Free PMC Article
  3. A modular network model of aging. Xue H, et al. Mol Syst Biol, 2007. PMID 18059442, Free PMC Article
  4. Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. Bates EA, et al. J Neurosci, 2006 Mar 8. PMID 16525063, Free PMC Article
  5. DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans. Reddien PW, et al. Genetics, 2007 Apr. PMID 17237514, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables histone deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in epigenetic regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Histone deacetylase domain-containing protein
NP_496910.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13882705..13888034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064509.7 → NP_496910.1  Histone deacetylase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496910.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U266
    Conserved Domains (1) summary
    cd10002
    Location:20 → 346
    HDAC10_HDAC6-dom1; Histone deacetylase 6, domain 1 and histone deacetylase 10
Nucleotide Protein
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