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hmg-1.1 HMG box domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175081, updated on 2-Nov-2024

Summary

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Official Symbol
hmg-1.1
Official Full Name
HMG box domain-containing protein
Primary source
WormBase:WBGene00001971
Locus tag
CELE_Y48B6A.14
See related
AllianceGenome:WB:WBGene00001971
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transcription cis-regulatory region binding activity. Predicted to be located in mitochondrion and nucleus. Is expressed in several structures, including pharynx; ventral nerve cord; and vulva. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hmg-1.1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (14250695..14251450)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Coiled-coil domain-containing protein 25 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PLP-1 binds nematode double-stranded telomeric DNA. Im SH, et al. Mol Cells, 2005 Oct 31. PMID 16267406
  2. Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Paek J, et al. Cell Metab, 2012 Oct 3. PMID 23040073, Free PMC Article
  3. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB, et al. PLoS Biol, 2012. PMID 22927794, Free PMC Article
  4. Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. Hammerquist AM, et al. Sci Rep, 2020 Nov 9. PMID 33168938, Free PMC Article
  5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
HMG box domain-containing protein
NP_001370073.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14250695..14251450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383989.2 → NP_001370073.1  HMG box domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EFV4
    Conserved Domains (1) summary
    cd01390
    Location:28 → 89
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
Nucleotide Protein
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