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elof-1 Transcription elongation factor 1 homolog [ Caenorhabditis elegans ]

Gene ID: 175090, updated on 2-Nov-2024

Summary

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Official Symbol
elof-1
Official Full Name
Transcription elongation factor 1 homolog
Primary source
WormBase:WBGene00013219
Locus tag
CELE_Y54G11A.11
See related
AllianceGenome:WB:WBGene00013219
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleolus. Orthologous to human ELOF1 (elongation factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See elof-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (14350153..14350798)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene FeS cluster biogenesis domain-containing protein Neighboring gene Protein lin-7 homolog Neighboring gene L51_S25_CI-B8 domain-containing protein Neighboring gene Glycogen debranching enzyme Neighboring gene pre-mRNA 3' end processing protein pfs-2 Neighboring gene SPK domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. Geijer ME, et al. Nat Cell Biol, 2021 Jun. PMID 34108662, Free PMC Article
  2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA polymerase II complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Transcription elongation factor 1 homolog
NP_496983.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14350153..14350798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064582.10 → NP_496983.1  Transcription elongation factor 1 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496983.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XVZ8
    Conserved Domains (1) summary
    pfam05129
    Location:6 → 79
    Elf1; Transcription elongation factor Elf1 like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XVZ8.1

Gene LinkOut

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