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catp-4 Sodium/potassium-transporting ATPase subunit alpha [ Caenorhabditis elegans ]

Gene ID: 175120, updated on 2-Nov-2024

Summary

Official Symbol
catp-4
Official Full Name
Sodium/potassium-transporting ATPase subunit alpha
Primary source
WormBase:WBGene00007248
Locus tag
CELE_C01G12.8
See related
AllianceGenome:WB:WBGene00007248
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See catp-4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (14593581..14597657)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Nematode Specific Peptide family, group B Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2;Trehalose-6-phosphate phosphatase C-terminal domain-containing protein Neighboring gene ShKT domain-containing protein Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type potassium transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables P-type sodium:potassium-exchanging transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in establishment or maintenance of transmembrane electrochemical gradient IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Sodium/potassium-transporting ATPase subunit alpha
NP_497034.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14593581..14597657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064633.5NP_497034.2  Sodium/potassium-transporting ATPase subunit alpha [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EFV6
    Conserved Domains (6) summary
    smart00831
    Location:2495
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    TIGR01106
    Location:91015
    ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
    pfam00122
    Location:118349
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:7911000
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam12710
    Location:582718
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:414507
    Cation_ATPase; Cation transport ATPase (P-type)