U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

atgp-2 Aamy domain-containing protein;Glycosyl hydrolase family 13 catalytic domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175125, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
atgp-2
Official Full Name
Aamy domain-containing protein;Glycosyl hydrolase family 13 catalytic domain-containing protein
Primary source
WormBase:WBGene00000225
Locus tag
CELE_C38C6.2
See related
AllianceGenome:WB:WBGene00000225
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Contributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See atgp-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (14640098..14644083, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene ncRNA Neighboring gene Serpentine receptor class epsilon-13 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Basement membrane proteoglycan;Basement membrane-specific heparan sulfate proteoglycan core protein;Ig-like domain-containing protein Neighboring gene Protein-cysteine N-palmitoyltransferase HHAT Neighboring gene DUF148 domain-containing protein;Phage protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Aromatic amino acid transporter AAT-9 of Caenorhabditis elegans localizes to neurons and muscle cells. Veljkovic E, et al. J Biol Chem, 2004 Nov 19. PMID 15364921
  2. The two C. elegans ATG-16 homologs have partially redundant functions in the basal autophagy pathway. Zhang H, et al. Autophagy, 2013 Dec. PMID 24185444, Free PMC Article
  3. Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters. Veljkovic E, et al. J Biol Chem, 2004 Feb 27. PMID 14668347
  4. Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans. Min H, et al. PLoS Genet, 2019 May. PMID 31125345, Free PMC Article
  5. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
contributes_to L-amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of amino acid transport complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Aamy domain-containing protein;Glycosyl hydrolase family 13 catalytic domain-containing protein
NP_001254435.1
  • Confirmed by transcript evidence
NP_001254436.1
  • Confirmed by transcript evidence
NP_001254437.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14640098..14644083 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267506.4 → NP_001254435.1  Glycosyl hydrolase family 13 catalytic domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254435.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45298
    Conserved Domains (2) summary
    pfam16028
    Location:78 → 135
    SLC3A2_N; Solute carrier family 3 member 2 N-terminus
    cl38930
    Location:130 → 553
    AmyAc_family; Alpha amylase catalytic domain family

  2. NM_001267507.3 → NP_001254436.1  Glycosyl hydrolase family 13 catalytic domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254436.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G1K108
    Conserved Domains (2) summary
    pfam16028
    Location:34 → 91
    SLC3A2_N; Solute carrier family 3 member 2 N-terminus
    cl38930
    Location:86 → 509
    AmyAc_family; Alpha amylase catalytic domain family

  3. NM_001267508.3 → NP_001254437.1  Aamy domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254437.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G1K110
    Conserved Domains (1) summary
    cl38930
    Location:1 → 97
    AmyAc_family; Alpha amylase catalytic domain family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools