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nhr-61 Nuclear hormone receptor family member nhr-61;Nuclear receptor [ Caenorhabditis elegans ]

Gene ID: 175142, updated on 2-Nov-2024

Summary

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Official Symbol
nhr-61
Official Full Name
Nuclear hormone receptor family member nhr-61;Nuclear receptor
Primary source
WormBase:WBGene00003651
Locus tag
CELE_W01D2.2
See related
AllianceGenome:WB:WBGene00003651
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nhr-61 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (14816136..14818543, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene 9.7 kDa protein Neighboring gene Organic solute transporter alpha-like protein 3 Neighboring gene Ribosomal protein L37 Neighboring gene Cadherin domain-containing protein Neighboring gene N-acetyltransferase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear hormone receptor family member nhr-61;Nuclear receptor
NP_001022381.1
  • Confirmed by transcript evidence
NP_001022382.1
  • Confirmed by transcript evidence
NP_001293577.1
  • Confirmed by transcript evidence
NP_001293578.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14816136..14818543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027211.6 → NP_001022382.1  Nuclear hormone receptor family member nhr-61 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022382.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GTF0
    Conserved Domains (2) summary
    cd06960
    Location:30 → 103
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    smart00430
    Location:208 → 380
    HOLI; Ligand binding domain of hormone receptors

  2. NM_001027210.8 → NP_001022381.1  Nuclear hormone receptor family member nhr-61 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022381.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O62389, Q9U355
    UniProtKB/TrEMBL
    Q5VKU2, Q9GTF0
    Conserved Domains (2) summary
    cd06960
    Location:30 → 103
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    smart00430
    Location:208 → 377
    HOLI; Ligand binding domain of hormone receptors

  3. NM_001306648.3 → NP_001293577.1  Nuclear receptor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293577.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PC05
    Conserved Domains (1) summary
    smart00430
    Location:114 → 283
    HOLI; Ligand binding domain of hormone receptors

  4. NM_001306649.3 → NP_001293578.1  Nuclear receptor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293578.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PMG4
    Conserved Domains (1) summary
    smart00430
    Location:114 → 286
    HOLI; Ligand binding domain of hormone receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O62389.2

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