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mrpl-40 Large ribosomal subunit protein mL40 [ Caenorhabditis elegans ]

Gene ID: 175174, updated on 2-Nov-2024

Summary

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Official Symbol
mrpl-40
Official Full Name
Large ribosomal subunit protein mL40
Primary source
WormBase:WBGene00018793
Locus tag
CELE_F54C4.1
See related
AllianceGenome:WB:WBGene00018793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrial ribosome. Is expressed widely. Used to study chromosome 22q11.2 deletion syndrome, distal. Orthologous to human MRPL40 (mitochondrial ribosomal protein L40). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mrpl-40 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (87559..89243)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene NAM-associated domain-containing protein Neighboring gene Integrin-linked protein kinase homolog pat-4 Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
  2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Large ribosomal subunit protein mL40
NP_497138.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    87559..89243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064737.6 → NP_497138.1  Large ribosomal subunit protein mL40 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497138.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TZ90
    Conserved Domains (1) summary
    pfam09812
    Location:28 → 170
    MRP-L28; Mitochondrial ribosomal protein L28
Nucleotide Protein
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