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affl-2 AF4/FMR2 C-terminal homology domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175203, updated on 2-Nov-2024

Summary

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Official Symbol
affl-2
Official Full Name
AF4/FMR2 C-terminal homology domain-containing protein
Primary source
WormBase:WBGene00021912
Locus tag
CELE_Y55B1BR.2
See related
AllianceGenome:WB:WBGene00021912
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in cytoplasm and nucleus. Is expressed widely. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See affl-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (434891..440142)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Stromal interaction molecule 1 Neighboring gene Chromo domain-containing protein Neighboring gene AFF-Like homolog Neighboring gene Transmembrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans. Hajdu-Cronin YM, et al. Genetics, 2004 Dec. PMID 15611166, Free PMC Article
  2. Caenorhabditis elegans AF4/FMR2 Family Homolog affl-2 Regulates Heat-Shock-Induced Gene Expression. Walton SJ, et al. Genetics, 2020 Aug. PMID 32518061, Free PMC Article
  3. A pathway for phagosome maturation during engulfment of apoptotic cells. Kinchen JM, et al. Nat Cell Biol, 2008 May. PMID 18425118, Free PMC Article
  4. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
  5. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AF4/FMR2 C-terminal homology domain-containing protein
NP_497199.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    434891..440142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064798.6 → NP_497199.1  AF4/FMR2 C-terminal homology domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497199.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95XW7
Nucleotide Protein
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