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Y54F10AL.1 GDT1 family protein [ Caenorhabditis elegans ]

Gene ID: 175368, updated on 2-Nov-2024

Summary

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Official Symbol
Y54F10AL.1
Official Full Name
GDT1 family protein
Primary source
WormBase:WBGene00021847
Locus tag
CELE_Y54F10AL.1
See related
AllianceGenome:WB:WBGene00021847
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion transmembrane transporter activity and manganese ion transmembrane transporter activity. Predicted to be involved in Golgi calcium ion homeostasis and metal ion transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including hypodermis; intestine; nervous system; pharyngeal gland cell; and reproductive system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIk. Orthologous to human TMEM165 (transmembrane protein 165). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y54F10AL.1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (2487710..2494340)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene TransThyretin-Related family domain Neighboring gene PIN domain-containing protein;PINc domain-containing protein Neighboring gene Putative phospholipase B-like 3 Neighboring gene Secreted protein Neighboring gene WD_REPEATS_REGION domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables manganese ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi calcium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in calcium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in manganese ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GDT1 family protein
NP_497567.1
  • Confirmed by transcript evidence
NP_497568.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2487710..2494340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065167.5 → NP_497568.1  GDT1 family protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497568.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9BL66
    Conserved Domains (1) summary
    COG2119
    Location:69 → 236
    Gdt1; Putative Ca2+/H+ antiporter, TMEM165/GDT1 family [General function prediction only]

  2. NM_065166.5 → NP_497567.1  GDT1 family protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497567.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZK9
    Conserved Domains (1) summary
    COG2119
    Location:69 → 294
    Gdt1; Putative Ca2+/H+ antiporter, TMEM165/GDT1 family [General function prediction only]
Nucleotide Protein
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