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gpa-17 G Protein, Alpha subunit [ Caenorhabditis elegans ]

Gene ID: 175377, updated on 2-Nov-2024

Summary

Official Symbol
gpa-17
Official Full Name
G Protein, Alpha subunit
Primary source
WormBase:WBGene00022196
Locus tag
CELE_Y71H2B.7
See related
AllianceGenome:WB:WBGene00022196
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See gpa-17 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (2586555..2589313)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol transfer protein Neighboring gene FTH domain-containing protein Neighboring gene AP complex subunit beta Neighboring gene ncRNA Neighboring gene Mediator of RNA polymerase II transcription subunit 19 Neighboring gene BTB domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta/gamma-subunit complex binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables guanyl nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in adenylate cyclase-activating dopamine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sensory perception of chemical stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
G Protein, Alpha subunit
NP_001367936.1
  • Product from WormBase gene class gpa;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2586555..2589313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001381782.2NP_001367936.1  G Protein, Alpha subunit [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4F4
    Conserved Domains (1) summary
    pfam00503
    Location:32395
    G-alpha; G-protein alpha subunit