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golg-4 GRIP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175445, updated on 2-Nov-2024

Summary

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Official Symbol
golg-4
Official Full Name
GRIP domain-containing protein
Primary source
WormBase:WBGene00010306
Locus tag
CELE_F59A2.6
See related
AllianceGenome:WB:WBGene00010306
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi vesicle transport. Predicted to be active in Golgi apparatus. Orthologous to human GOLGA4 (golgin A4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See golg-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
18
Sequence:
Chromosome: III; NC_003281.10 (3405568..3425468)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Pre-mRNA cleavage complex subunit Clp1 C-terminal domain-containing protein;Protein clpf-1 Neighboring gene Nuclear Pore complex Protein Neighboring gene ACT domain-containing protein Neighboring gene ncRNA Neighboring gene protein-histidine N-methyltransferase Neighboring gene tRNA-Lys Neighboring gene ncRNA Neighboring gene Spaetzle domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans. Khan LA, et al. Biochem Biophys Res Commun, 2008 Apr 11. PMID 18261464
  2. The golgin coiled-coil proteins of the Golgi apparatus. Munro S. Cold Spring Harb Perspect Biol, 2011 Jun 1. PMID 21436057, Free PMC Article
  3. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article
  4. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. Wang X, et al. J Cell Biol, 2022 Jul 4. PMID 35604368, Free PMC Article
  5. Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome. Shen X, et al. Cell Calcium, 2008 May. PMID 17854888

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi vesicle transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GRIP domain-containing protein
NP_001355507.1
  • Confirmed by transcript evidence
NP_001355508.1
  • Confirmed by transcript evidence
NP_001355509.1
  • Confirmed by transcript evidence
NP_001355510.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3405568..3425468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001368620.3 → NP_001355510.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6PAV3
    Conserved Domains (4) summary
    PTZ00121
    Location:261 → 959
    PTZ00121; MAEBL; Provisional
    smart00755
    Location:1502 → 1550
    Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
    TIGR02168
    Location:535 → 1412
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR04211
    Location:1374 → 1479
    SH3_and_anchor; SH3 domain protein

  2. NM_001368617.3 → NP_001355507.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6PCP8
    Conserved Domains (4) summary
    smart00755
    Location:1572 → 1620
    Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
    TIGR02168
    Location:577 → 1442
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR04211
    Location:1444 → 1549
    SH3_and_anchor; SH3 domain protein
    pfam12128
    Location:207 → 884
    DUF3584; Protein of unknown function (DUF3584)

  3. NM_001368619.3 → NP_001355509.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6NI91
    Conserved Domains (4) summary
    smart00755
    Location:1530 → 1578
    Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
    COG1196
    Location:160 → 458
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:535 → 1400
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR04211
    Location:1402 → 1507
    SH3_and_anchor; SH3 domain protein

  4. NM_001368618.3 → NP_001355508.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3P6N624
    Conserved Domains (4) summary
    smart00755
    Location:1544 → 1592
    Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
    TIGR02168
    Location:577 → 1454
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR04211
    Location:1416 → 1521
    SH3_and_anchor; SH3 domain protein
    pfam12128
    Location:207 → 884
    DUF3584; Protein of unknown function (DUF3584)
Nucleotide Protein
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