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cpg-1 Chondroitin proteoglycan 1 [ Caenorhabditis elegans ]

Gene ID: 175586, updated on 2-Nov-2024

Summary

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Official Symbol
cpg-1
Official Full Name
Chondroitin proteoglycan 1
Primary source
WormBase:WBGene00000465
Locus tag
CELE_C07G2.1
See related
AllianceGenome:WB:WBGene00000465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure. Is expressed in eggshell; germ line; and oocyte. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cpg-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (4489359..4491392)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Small ribosomal subunit protein eS1 Neighboring gene Insulin-like peptide 17 Neighboring gene Transcription factor atf-7 Neighboring gene ncRNA Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development. Lee MH, et al. Genes Dev, 2001 Sep 15. PMID 11562350, Free PMC Article
  2. Hierarchical assembly of the eggshell and permeability barrier in C. elegans. Olson SK, et al. J Cell Biol, 2012 Aug 20. PMID 22908315, Free PMC Article
  3. The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo. Johnston WL, et al. BMC Biol, 2006 Oct 16. PMID 17042944, Free PMC Article
  4. Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. Olson SK, et al. J Cell Biol, 2006 Jun 19. PMID 16785326, Free PMC Article
  5. Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase. Bembenek JN, et al. Development, 2007 Nov. PMID 17913784, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Chondroitin chains on CPG-1 and CPG-2 proteoglycans are required for cytokinesis.
    Title: Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2.
  2. Chondroitin chains on CEJ-1 proteoglycans are required for cytokinesis.
    Title: Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chitin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in eggshell formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in eggshell formation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cytokinesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in external encapsulating structure IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Chondroitin proteoglycan 1
NP_001021159.1
  • Confirmed by transcript evidence
NP_001021160.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4489359..4491392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001025988.8 → NP_001021159.1  Chondroitin proteoglycan 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021159.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17802, Q1A3T6
    Conserved Domains (1) summary
    pfam01607
    Location:214 → 266
    CBM_14; Chitin binding Peritrophin-A domain

  2. NM_001025989.5 → NP_001021160.1  Chondroitin proteoglycan 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021160.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17802
    Conserved Domains (1) summary
    pfam01607
    Location:61 → 113
    CBM_14; Chitin binding Peritrophin-A domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q17802.1

Gene LinkOut

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