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pan-1 P-granule-associated novel protein 1 [ Caenorhabditis elegans ]

Gene ID: 175596, updated on 2-Nov-2024

Summary

Official Symbol
pan-1
Official Full Name
P-granule-associated novel protein 1
Primary source
WormBase:WBGene00003915
Locus tag
CELE_M88.6
See related
AllianceGenome:WB:WBGene00003915
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables DEAD/H-box RNA helicase binding activity. Involved in germ cell development and molting cycle. Located in P granule and plasma membrane. Is expressed in several structures, including body wall musculature; gonad; hypodermis; intestine; and somatic nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See pan-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (4562738..4566283)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene K Homology domain-containing protein Neighboring gene Malonyl-CoA decarboxylase, mitochondrial Neighboring gene Isocitrate dehydrogenase [NAD] subunit, mitochondrial Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DEAD/H-box RNA helicase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell development IEA
Inferred from Electronic Annotation
more info
 
involved_in germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in molting cycle, collagen and cuticulin-based cuticle IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
P-granule-associated novel protein 1
NP_001293622.1
  • Partially confirmed by transcript evidence
NP_497924.2
  • Confirmed by transcript evidence
NP_497925.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4562738..4566283
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065524.6NP_497925.1  P-granule-associated novel protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497925.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21604, Q9U3A0, S6FWR2
    Conserved Domains (3) summary
    cd00116
    Location:80326
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:130152
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:199259
    LRR_8; Leucine rich repeat
  2. NM_065523.8NP_497924.2  P-granule-associated novel protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497924.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9U3A0
    Conserved Domains (4) summary
    cd00116
    Location:11125
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:1235
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:3483
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:1178
    LRR_8; Leucine rich repeat
  3. NM_001306693.3NP_001293622.1  P-granule-associated novel protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293622.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9U3A0