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cee-1 Conserved Edge Expressed protein [ Caenorhabditis elegans ]

Gene ID: 175658, updated on 2-Nov-2024

Summary

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Official Symbol
cee-1
Official Full Name
Conserved Edge Expressed protein
Primary source
WormBase:WBGene00017825
Locus tag
CELE_F26F4.1
See related
AllianceGenome:WB:WBGene00017825
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein insertion into ER membrane. Predicted to be part of BAT3 complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human GET4 (guided entry of tail-anchored proteins factor 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cee-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (4912699..4914133)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Rhomboid-related protein 1 Neighboring gene ANK_REP_REGION domain-containing protein Neighboring gene DUF3149 domain-containing protein;Glutaredoxin domain-containing protein Neighboring gene PDZ domain-containing protein Neighboring gene arginine--tRNA ligase;putative arginine--tRNA ligase, cytoplasmic Neighboring gene putative DNA-directed RNA polymerases I, II, and III subunit RPABC3 Neighboring gene NEDD8-activating enzyme E1 regulatory subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The C. elegans glycopeptide hormone receptor ortholog, FSHR-1, regulates germline differentiation and survival. Cho S, et al. Curr Biol, 2007 Feb 6. PMID 17276913
  2. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  3. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  4. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein insertion into ER membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein insertion into ER membrane IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of BAT3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Conserved Edge Expressed protein
NP_498034.1
  • Product from WormBase gene class cee;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4912699..4914133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065633.11 → NP_498034.1  Conserved Edge Expressed protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498034.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19824
    Conserved Domains (1) summary
    pfam04190
    Location:42 → 289
    DUF410; Protein of unknown function (DUF410)
Nucleotide Protein
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