sax-2 MOR2-PAG1_N domain-containing protein;Protein furry C-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: sax-2
Official Full Name: MOR2-PAG1_N domain-containing protein;Protein furry C-terminal domain-containing protein
Primary source: WormBase:WBGene00004728
Locus tag: CELE_F21H11.2
See related: AllianceGenome:WB:WBGene00004728
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in neuron projection development. Predicted to be active in cell cortex and site of polarized growth. Is expressed in head neurons; tail neurons; and ventral nerve cord. Orthologous to human FRYL (FRY like transcription coactivator) and FRY (FRY microtubule binding protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sax-2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 34

Sequence:: Chromosome: III; NC_003281.10 (5109701..5130676)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F21H11.2 (e-PCR)
- UniSTS:306192

F21H11.1 (e-PCR)
- UniSTS:316598

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in cell morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in neuron projection development	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron projection development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cell cortex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in site of polarized growth	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: MOR2-PAG1_N domain-containing protein;Protein furry C-terminal domain-containing protein

NP_741131.2

Confirmed by transcript evidence

NP_741132.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

5109701..5130676

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_171117.5 → NP_741131.2 MOR2-PAG1_N domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741131.2

Status: REVIEWED

UniProtKB/TrEMBL

Q5DX48, Q5UBX5

Conserved Domains (2) summary

pfam14222
Location:154 → 682

MOR2-PAG1_N; Cell morphogenesis N-terminal

pfam14225
Location:1944 → 2201

MOR2-PAG1_C; Cell morphogenesis C-terminal
NM_171118.6 → NP_741132.2 Protein furry C-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741132.2

Status: REVIEWED

UniProtKB/TrEMBL

H2KZU6