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wdr-37 WD repeat-containing protein 37 [ Caenorhabditis elegans ]

Gene ID: 175774, updated on 2-Nov-2024

Summary

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Official Symbol
wdr-37
Official Full Name
WD repeat-containing protein 37
Primary source
WormBase:WBGene00015470
Locus tag
CELE_C05D2.10
See related
AllianceGenome:WB:WBGene00015470
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Human ortholog(s) of this gene implicated in neurooculocardiogenitourinary syndrome. Orthologous to human WDR37 (WD repeat domain 37). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See wdr-37 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (5597979..5600058, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cytochrome b-c1 complex subunit 1, mitochondrial;Peptidase M16 C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Cell death protein 6 Neighboring gene MADF domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
WD repeat-containing protein 37
NP_001379621.1
  • Confirmed by transcript evidence
NP_498204.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5597979..5600058 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392101.1 → NP_001379621.1  WD repeat-containing protein 37 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95X41
    Conserved Domains (3) summary
    cd00200
    Location:129 → 390
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    PTZ00420
    Location:305 → 484
    PTZ00420; coronin; Provisional
    sd00039
    Location:184 → 276
    7WD40; WD40 repeat [structural motif]

  2. NM_065803.5 → NP_498204.1  WD repeat-containing protein 37 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498204.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95X42
    Conserved Domains (3) summary
    cd00200
    Location:131 → 392
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    PTZ00420
    Location:307 → 486
    PTZ00420; coronin; Provisional
    sd00039
    Location:186 → 278
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
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