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Y42G9A.3 L domain-like protein;Leucine-rich repeat-containing protein 58 [ Caenorhabditis elegans ]

Gene ID: 175865, updated on 2-Nov-2024

Summary

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Official Symbol
Y42G9A.3
Official Full Name
L domain-like protein;Leucine-rich repeat-containing protein 58
Primary source
WormBase:WBGene00021533
Locus tag
CELE_Y42G9A.3
See related
AllianceGenome:WB:WBGene00021533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in intracellular signal transduction. Is expressed in hypodermis and intestine. Orthologous to human LRRC58 (leucine rich repeat containing 58). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y42G9A.3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (6146258..6148065)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Glycylpeptide N-tetradecanoyltransferase;putative glycylpeptide N-tetradecanoyltransferase Neighboring gene Serine/threonine-protein kinase SULU Neighboring gene GHMP kinase C-terminal domain-containing protein;MeValonate Kinase;Mevalonate kinase Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA Neighboring gene Secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
L domain-like protein;Leucine-rich repeat-containing protein 58
NP_001022864.1
  • Confirmed by transcript evidence
NP_001022865.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6146258..6148065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027694.7 → NP_001022865.1  L domain-like protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022865.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86DD0
    Conserved Domains (3) summary
    cd00116
    Location:94 → 275
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:34 → 62
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:199 → 256
    LRR_8; Leucine rich repeat

  2. NM_001027693.9 → NP_001022864.1  Leucine-rich repeat-containing protein 58 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022864.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4Z5
    Conserved Domains (3) summary
    cd00116
    Location:94 → 275
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:34 → 62
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:199 → 256
    LRR_8; Leucine rich repeat
Nucleotide Protein
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