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F47D12.9 WD_REPEATS_REGION domain-containing protein;putative WD repeat-containing protein F47D12.9 [ Caenorhabditis elegans ]

Gene ID: 175892, updated on 2-Nov-2024

Summary

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Official Symbol
F47D12.9
Official Full Name
WD_REPEATS_REGION domain-containing protein;putative WD repeat-containing protein F47D12.9
Primary source
WormBase:WBGene00018564
Locus tag
CELE_F47D12.9
See related
AllianceGenome:WB:WBGene00018564
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF4 (DDB1 and CUL4 associated factor 4); DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1); and DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F47D12.9 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (6299332..6302507, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Kelch repeat and BTB domain-containing protein F47D12.7 Neighboring gene Uncharacterized protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein;Muscarinic acetylcholine receptor gar-2 Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
WD_REPEATS_REGION domain-containing protein;putative WD repeat-containing protein F47D12.9
NP_001370865.1
  • Confirmed by transcript evidence
NP_498382.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6299332..6302507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065981.7 → NP_498382.2  putative WD repeat-containing protein F47D12.9 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498382.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09392
    Conserved Domains (3) summary
    COG2319
    Location:369 → 511
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:465 → 504
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:432 → 512
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_001382890.2 → NP_001370865.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I7J9
    Conserved Domains (2) summary
    COG2319
    Location:236 → 378
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:332 → 371
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09392.1

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