znf-622 C2H2-type domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: znf-622
Official Full Name: C2H2-type domain-containing protein
Primary source: WormBase:WBGene00015809
Locus tag: CELE_C16A3.4
See related: AllianceGenome:WB:WBGene00015809
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Is expressed in intestine; pharynx; and tail. Orthologous to human ZNF622 (zinc finger protein 622). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See znf-622 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (6381634..6382996)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C16A3.4 (e-PCR)
- UniSTS:308570

C16A3.6 (e-PCR)
- UniSTS:308571

C16A3.5 (e-PCR)
- UniSTS:320687

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ribosomal large subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of preribosome, large subunit precursor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: C2H2-type domain-containing protein

NP_498397.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

6381634..6382996

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065996.5 → NP_498397.1 C2H2-type domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498397.1

Status: REVIEWED

UniProtKB/TrEMBL

Q18037

Conserved Domains (3) summary

smart00451
Location:68 → 101

ZnF_U1; U1-like zinc finger

sd00020
Location:9 → 31

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam12756
Location:164 → 263

zf-C2H2_2; C2H2 type zinc-finger (2 copies)