U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

odr-4 Odorant response abnormal protein 4 [ Caenorhabditis elegans ]

Gene ID: 175950, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
odr-4
Official Full Name
Odorant response abnormal protein 4
Primary source
WormBase:WBGene00003851
Locus tag
CELE_Y102E9.1
See related
AllianceGenome:WB:WBGene00003851
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle. Part of protein-containing complex. Is expressed in neurons. Orthologous to human ODR4 (odr-4 GPCR localization factor homolog). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See odr-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (6730800..6733936)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit Neighboring gene tRNA-Arg Neighboring gene Uncharacterized protein Neighboring gene HMA domain-containing protein Neighboring gene SEA domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Sensory interaction between attractant diacetyl and repellent 2-nonanone in the nematode Caenorhabditis elegans. Matsuura T, et al. J Exp Zool A Ecol Genet Physiol, 2013 Jun. PMID 23580469
  2. Trafficking prerogatives of olfactory receptors. McClintock TS, et al. Neuroreport, 2003 Aug 26. PMID 14502073
  3. Neural circuit-dependent odor adaptation in C. elegans is regulated by the Ras-MAPK pathway. Hirotsu T, et al. Genes Cells, 2005 Jun. PMID 15938711
  4. Chemosensation: molecular mechanisms in worms and mammals. Prasad BC, et al. Trends Genet, 1999 Apr. PMID 10203825
  5. Behavioral motifs and neural pathways coordinating O2 responses and aggregation in C. elegans. Rogers C, et al. Curr Biol, 2006 Apr 4. PMID 16581509

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ODR-4 also binds ODR-10, suggesting that an ODR-4/ODR-8 complex promotes GPCR folding, maturation, or export from the ER.
    Title: An ER complex of ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by a Ufm1-independent mechanism.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in chemosensory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
  
involved_in olfactory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to non-motile cilium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in receptor localization to non-motile cilium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to odorant IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in axon IEA
Inferred from Electronic Annotation
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in dendrite IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in transport vesicle membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Odorant response abnormal protein 4
NP_001022815.1
  • Confirmed by transcript evidence
NP_001370710.1
  • Confirmed by transcript evidence
NP_001379932.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6730800..6733936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392129.1 → NP_001379932.1  Odorant response abnormal protein 4 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O61648, Q23233, Q8I7F7, Q8I7F8
    Conserved Domains (1) summary
    pfam14778
    Location:66 → 410
    ODR4-like; Olfactory receptor 4-like

  2. NM_001027644.9 → NP_001022815.1  Odorant response abnormal protein 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022815.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8I7F8
    Conserved Domains (1) summary
    pfam14778
    Location:64 → 408
    ODR4-like; Olfactory receptor 4-like

  3. NM_001382900.2 → NP_001370710.1  Odorant response abnormal protein 4 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam14778
    Location:34 → 380
    ODR4-like; Olfactory receptor 4-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8I7F8.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools