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sap-140 U2 snRNP-associated SURP motif-containing protein [ Caenorhabditis elegans ]

Gene ID: 176063, updated on 2-Nov-2024

Summary

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Official Symbol
sap-140
Official Full Name
U2 snRNP-associated SURP motif-containing protein
Primary source
WormBase:WBGene00015581
Locus tag
CELE_C07H6.4
See related
AllianceGenome:WB:WBGene00015581
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to be active in nucleus. Orthologous to human U2SURP (U2 snRNP associated SURP domain containing). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sap-140 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (7499738..7503241)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase cgh-1 Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class Z Neighboring gene Protein CLASP-1 Neighboring gene Telomere length regulation protein clk-2 Neighboring gene RRM domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
U2 snRNP-associated SURP motif-containing protein
NP_498648.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7499738..7503241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066247.7 → NP_498648.1  U2 snRNP-associated SURP motif-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498648.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95YF1
    Conserved Domains (3) summary
    cd12223
    Location:199 → 282
    RRM_SR140; RNA recognition motif (RRM) in U2-associated protein SR140 and similar proteins
    pfam01805
    Location:366 → 416
    Surp; Surp module
    cl02544
    Location:529 → 665
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
Nucleotide Protein
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