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ZK686.2 Putative ATP-dependent RNA helicase ZK686.2 [ Caenorhabditis elegans ]

Gene ID: 176088, updated on 2-Nov-2024

Summary

Official Symbol
ZK686.2
Official Full Name
Putative ATP-dependent RNA helicase ZK686.2
Primary source
WormBase:WBGene00022792
Locus tag
CELE_ZK686.2
See related
AllianceGenome:WB:WBGene00022792
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be located in P granule. Predicted to be active in nucleus. Is expressed in neurons. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ZK686.2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (7763720..7766052, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Putative serine protease pcp-1 Neighboring gene Metaxin-2 homolog Neighboring gene Putative zinc finger protein ZK686.5 Neighboring gene putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in P granule IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Putative ATP-dependent RNA helicase ZK686.2
NP_498690.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7763720..7766052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066289.7NP_498690.2  Putative ATP-dependent RNA helicase ZK686.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498690.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34668
    Conserved Domains (3) summary
    smart00487
    Location:130352
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:371502
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:135330
    DEAD; DEAD/DEAH box helicase