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vms-1 tRNA endonuclease vms-1 [ Caenorhabditis elegans ]

Gene ID: 176141, updated on 2-Nov-2024

Summary

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Official Symbol
vms-1
Official Full Name
tRNA endonuclease vms-1
Primary source
WormBase:WBGene00019457
Locus tag
CELE_K06H7.3
See related
AllianceGenome:WB:WBGene00019457
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable endonuclease activity and metal ion binding activity. Predicted to be involved in ERAD pathway. Located in cytoplasm and dendrite. Is expressed in amphid neurons; head neurons; intestine; tail neurons; and ventral nerve cord. Orthologous to human ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See vms-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
11
Sequence:
Chromosome: III; NC_003281.10 (8088535..8091601)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Anaphase-promoting complex subunit 2 Neighboring gene Uncharacterized protein Neighboring gene GTP exchange factor for ARFs 1 Neighboring gene isopentenyl-diphosphate Delta-isomerase Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A stress-responsive system for mitochondrial protein degradation. Heo JM, et al. Mol Cell, 2010 Nov 12. PMID 21070972, Free PMC Article
  2. Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans. Gaeta AL, et al. PLoS Genet, 2022 Aug. PMID 35984862, Free PMC Article
  3. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950
  4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
  5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tRNA endonuclease vms-1
NP_498765.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8088535..8091601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066364.8 → NP_498765.1  tRNA endonuclease vms-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498765.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34511
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34511.2

Gene LinkOut

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