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R05D3.6 Putative ATP synthase subunit epsilon, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 176178, updated on 2-Nov-2024

Summary

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Official Symbol
R05D3.6
Official Full Name
Putative ATP synthase subunit epsilon, mitochondrial
Primary source
WormBase:WBGene00019880
Locus tag
CELE_R05D3.6
See related
AllianceGenome:WB:WBGene00019880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Orthologous to human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See R05D3.6 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (8350419..8350805, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Colicin V production protein Neighboring gene pseudo Neighboring gene Kinesin heavy chain Neighboring gene Putative RNA-binding protein R05D3.8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Haynes CM, et al. Mol Cell, 2010 Feb 26. PMID 20188671, Free PMC Article
  2. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
  
enables proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ATP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven mitochondrial ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting ATP synthase complex, catalytic core F(1) IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative ATP synthase subunit epsilon, mitochondrial
NP_001380031.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8350419..8350805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392153.1 → NP_001380031.1  Putative ATP synthase subunit epsilon, mitochondrial [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34539
    Conserved Domains (1) summary
    pfam04627
    Location:3 → 47
    ATP-synt_Eps; Mitochondrial ATP synthase epsilon chain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34539.1

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials