U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

R08D7.4 Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176269, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
R08D7.4
Official Full Name
Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein
Primary source
WormBase:WBGene00011144
Locus tag
CELE_R08D7.4
See related
AllianceGenome:WB:WBGene00011144
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be part of protein-containing complex. Orthologous to several human genes including EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase) and FAM86B2 (family with sequence similarity 86 member B2). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See R08D7.4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (8971892..8973671)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene BUD13 homolog Neighboring gene Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 Neighboring gene Eukaryotic translation initiation factor 3 subunit D Neighboring gene putative calcium-binding protein R08D7.5 Neighboring gene putative 3',5'-cyclic phosphodiesterase pde-2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein-lysine N-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein
NP_001379047.1
  • Confirmed by transcript evidence
NP_001379488.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8971892..8973671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392169.1 → NP_001379047.1  Complex1_LYR_dom domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P30643
    Conserved Domains (1) summary
    cl17173
    Location:165 → 314
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. NM_001392168.1 → NP_001379488.1  Complex 1 LYR protein domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B2MZB2
    Conserved Domains (1) summary
    cd20261
    Location:9 → 82
    Complex1_LYR_LYRM1; LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 1 (LYRM1) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P30643.3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools