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T02C1.2 RING-type E3 ubiquitin transferase [ Caenorhabditis elegans ]

Gene ID: 176306, updated on 2-Nov-2024

Summary

Official Symbol
T02C1.2
Official Full Name
RING-type E3 ubiquitin transferase
Primary source
WormBase:WBGene00011366
Locus tag
CELE_T02C1.2
See related
AllianceGenome:WB:WBGene00011366
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable nucleosome binding activity and ubiquitin-protein transferase activity. Predicted to be involved in double-strand break repair. Predicted to be located in membrane. Predicted to be active in nucleus and site of double-strand break. Orthologous to human RNF169 (ring finger protein 169). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See T02C1.2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (9251029..9253126)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Sodium-dependent dopamine transporter Neighboring gene putative RING finger protein T02C1.1 Neighboring gene Uncharacterized protein Neighboring gene CAP-Gly domain-containing linker protein 1 homolog Neighboring gene ncRNA

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
RING-type E3 ubiquitin transferase
NP_001022740.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    9251029..9253126
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027569.4NP_001022740.2  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022740.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YWU1
    Conserved Domains (2) summary
    cd00162
    Location:100137
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl17238
    Location:96137
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain