C38H2.2 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C38H2.2
Official Full Name: Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Primary source: WormBase:WBGene00008019
Locus tag: CELE_C38H2.2
See related: AllianceGenome:WB:WBGene00008019
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is expressed in several structures, including intestine; nervous system; pharynx; rectal gland cell; and reproductive system. Orthologous to human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C38H2.2 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 8

Sequence:: Chromosome: III; NC_003281.10 (10381773..10385335)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cloning and enzymatic characterization of T-synthase from C. elegans (Ce-T-synthase), a functional ortholog to the human T-synthase in generating core 1 O-glycans .
Title: Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C38H2.2 (e-PCR)
- UniSTS:306767

STS3-18 (e-PCR)
- UniSTS:242023

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

NP_499293.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

10381773..10385335

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066892.11 → NP_499293.2 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499293.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18515, Q9GQC5

Conserved Domains (1) summary

cl21608
Location:106 → 274

Galactosyl_T; Galactosyltransferase