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D2045.8 BTB domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176468, updated on 2-Nov-2024

Summary

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Official Symbol
D2045.8
Official Full Name
BTB domain-containing protein
Primary source
WormBase:WBGene00008425
Locus tag
CELE_D2045.8
See related
AllianceGenome:WB:WBGene00008425
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein homooligomerization. Orthologous to human TNFAIP1 (TNF alpha induced protein 1); KCTD10 (potassium channel tetramerization domain containing 10); and KCTD13 (potassium channel tetramerization domain containing 13). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See D2045.8 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (10482288..10483943)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase 25 family member Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA Neighboring gene SSD domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. Xu L, et al. Nature, 2003 Sep 18. PMID 13679922
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BTB domain-containing protein
NP_499312.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10482288..10483943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066911.7 → NP_499312.2  BTB domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499312.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18986
    Conserved Domains (1) summary
    cl38908
    Location:7 → 97
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein
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